Research Studies


Start Date
January 2016
End Date
March 2018
Co-ordinated by
University of Liverpool and Alder Hey Children’s NHS Foundation Trust
Local PI
Dr Chris Gough
Lead Research Practitioner
Sonya Finucane

This trial was looking at the use of intravenous (administered through a drip in the arm) levetiracetam versus intravenous phenytoin in non-terminating acute, prolonged tonic–clonic seizures including convulsive status epilepticus in children. This was an open label study (we knew what was being given). The study aimed to see which open label drug terminates seizures more effectively in order to see if treatment should be streamlined to one drug across the NHS. It is important as currently different NHS Trusts use one or the other drug and there is no national protocol for status epilepticus in the UK.

The results of this study are available here: